White Dwarf dual

Laser for 3-photon deep-tissue imaging with red and green markers

wavelength: 1300 nm and 1700 nm
average power: > 3 W or > 5 W
optimized for multicolor deep imaging
based on industrial Yb-fiber femtosecond laser

Introduction

High performance femtosecond laser for three-photon microscopy (3p microscopy)

The White Dwarf is a femtosecond laser system specially designed for three-photon microscopy offering highest performance and robustness.

The White Dwarf is a compact and robust femtosecond laser system specially designed for 3-photon microscopy, offering now simultaneously 1300 and 1700 nm at outstanding performance parameters. With the highest peak power available for 3-photon microscopy, the White Dwarf allows neuroscientists to image deeper, faster and at better resolution than ever before at green and red fluorescent markers.

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Features

Optimized for multi-color imaging

Two simultaneous outputs at 1300 and 1700 nm

Ideal for deep imaging

> 5 W average power after compressor

Proven in the field

Trusted by 20+ neuroscience labs worldwide

Reliability

Robust design and one-box system

1035 nm output

Output for optogenetics optionally available

Specs

	WD-1300-1700	WD-1300-1700-pro
Central wavelength	1300 nm and 1700 nm (switchable or simultaneous)	1300 nm and 1700 nm (switchable or simultaneous)
Average power	> 3 W	> 5 W
Pulse duration FWHM	< 50 fs at 1300 nm and < 65 fs at 1700 nm	< 50 fs at 1300 nm and < 65 fs at 1700 nm
Dispersion compensation optional	up to -12.000 fs^2 at 1300 nm and up to +/-4.000 fs^2 at 1700 nm	up to -12.000 fs^2 at 1300 nm and up to +/-4.000 fs^2 at 1700 nm
Pulse energy compressed	> 3 µJ at 1 MHz	> 5 µJ at 1 MHz
Repetition rate	up to 2 MHz	up to 2 MHz
Beam quality M2	< 1.3	< 1.3
Power stability 12 hrs	< 1 %	< 1 %
Dimensions	80 cm x 120 cm	80 cm x 120 cm
Pump laser incl.	Coherent Monaco 40 W	Coherent Monaco 60 W

Performance

Applications

Multiphoton microscopy
Volumetric brain imaging
Multi-color imaging
Adaptive optics (AO) three-photon microscopy

Downloads

FAQ

Do you have customer references?

Yes, the White Dwarf is already installed and tested by many labs. Please contact us, we are happy to share specific references to your application. You can find a first overview of scientific publications from our users below.

How many outputs does the White Dwarf dual provide?

The White Dwarf dual can offer up to three outputs: 1300 nm, 1700 nm and 1035 nm. The system can be designed to offer all outputs simultaneously or switchable between different outputs. Please contact us for customization options.

At which repetition rate does the White Dwarf dual operate?

Our White Dwarf dual version can be configured at any single repetition rate between 1 and 2 MHz. The maximum average power is available at the configured repetition rate. Lower repetition rates can be chosen using the built-in pulse-picker. This provides a constant pulse energy at correspondingly lower average power. Example: WhiteDwarf operating at 2 MHz and 2.5 µJ delivers 5 W; it can be down-picked to 1 MHz and 2.5 µJ delivering 2.5 W.

Who installs the White Dwarf?

Our service team will install the pump laser and the OPCPA at the customer’s site. Users will receive training on the operation of the White Dwarf.

Is the pump laser included in the White Dwarf?

Yes, we offer the full package including pump laser and OPCPA. The pump laser is integrated into the OPCPA housing on a shared thermally managed breadboard offering a robust one-box solution.

Publications

May 2, 2019

Weisenburger et al., Volumetric Ca2+ Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy, Cell (2019)

https://doi.org/10.1016/j.cell.2019.03.011
September 30, 2021

Streich, L., Boffi, J.C., Wang, L. et al. High-resolution structural and functional deep brain imaging using adaptive optics three-photon microscopy. Nat Methods 18, 1253–1258 (2021).

https://doi.org/10.1038/s41592-021-01257-6
December 21, 2023

Amr Tamimi, Martin Caldarola,…, Robert Prevedel, Deep mouse brain two-photon near-infrared fluorescence imaging using a superconducting nanowire single-photon detector array

https://doi.org/10.48550/arXiv.2312.14042