High performance laser for two-photon and three-photon microscopy
The White Dwarf is a laser system specially designed for multi-photon microscopy offering highest performance and robustness.
The White Dwarf is a compact and robust laser system specially designed for multi-photon microscopy, offering now simultaneously 960 and 1300 nm at outstanding performance parameters. With the highest peak power available for hybrid multi-photon microscopy, the White Dwarf allows neuroscientists to image deeper, faster and at better resolution than ever before.
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Yes, the White Dwarf is already installed and tested by many labs. Please contact us, we are happy to share specific references to your application. You can find a first overview of scientific publications from our users below.
The White Dwarf hybrid can offer up to three outputs: 960 nm, 1300 nm and 1035 nm. The outputs can be configured to operate simultaneously or to be switchable. Please contact us for customization options.
Our White Dwarf hybrid version can be configured at any single repetition rate between 1 and 5 MHz. The maximum average power is available at the configured repetition rate. Lower repetition rates can be chosen using the built-in pulse-picker. This provides a constant pulse energy at correspondingly lower average power. Example: White Dwarf operating at 2 MHz and 2.5 µJ delivers 5 W; it can be down-picked to 1 MHz and 2.5 µJ delivering 2.5 W.
Yes, we offer the full package including pump laser and OPCPA. The pump laser is integrated into the OPCPA housing on a shared thermally managed breadboard offering a robust one-box solution.
Publications
May 2, 2019
Weisenburger et al., Volumetric Ca2+ Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy, Cell (2019)
Streich, L., Boffi, J.C., Wang, L. et al. High-resolution structural and functional deep brain imaging using adaptive optics three-photon microscopy. Nat Methods 18, 1253–1258 (2021).
Jason Manley, Jeffrey Demas, Hyewon Kim, Francisca Martínez Traub, Alipasha Vaziri, Simultaneous, cortex-wide dynamics of up to 1 million neurons reveal unbounded scaling of dimensionality with neuron number, Neuron 2024
Che-Hang Yu, Yiyi Yu,…, Alipasha Vaziri,…, David Fitzpatrick,…, Prakash Kara,…, Ikuko T. Smith & Spencer LaVere Smith, The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo, Nature Methods 2023
