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White Dwarf hybrid

Laser for simultaneous 2-photon and 3-photon imaging
  • wavelength: 960 nm and 1300 nm
  • average power: > 3 W or > 5 W
  • optimized for hybrid microscopy
  • based on industrial Yb femtosecond laser
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Details
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Introduction

High performance laser for two-photon and three-photon microscopy

The White Dwarf is a laser system specially designed for multi-photon microscopy offering highest performance and robustness.

The White Dwarf is a compact and robust laser system specially designed for multi-photon microscopy, offering now simultaneously 960 and 1300 nm at outstanding performance parameters. With the highest peak power available for hybrid multi-photon microscopy, the White Dwarf allows neuroscientists to image deeper, faster and at better resolution than ever before.

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Features

Optimized for hybrid microscopy (2p/3p)

Two simultaneous outputs at 960 nm and 1300 nm

Ideal for deep imaging

> 5 W average power after compressor

Proven in the field

Trusted by 20+ neuroscience labs worldwide

Reliability

Robust one-box design

1035 nm output

Output for optogenetics optionally available

Specs

WD-1300-960 WD-1300-960-pro
Central wavelength 960 nm and 1300 nm (switchable or simultaneous) 960 nm and 1300 nm (switchable or simultaneous)
Average power > 3 W > 5 W
Pulse duration
FWHM		 < 100 fs at 960 nm and < 50 fs at 1300 nm < 100 fs at 960 nm and < 50 fs at 1300 nm
Dispersion compensation
optional		 up to -20.000 fs^2 at 960 nm and up to -12.000 fs^2 at 1300 nm up to -20.000 fs^2 at 960 nm and up to -12.000 fs^2 at 1300 nm
Pulse energy
compressed		 > 3 µJ at 1 MHz > 5 µJ at 1 MHz
Repetition rate up to 5 MHz up to 5 MHz
Beam quality M2 < 1.3 < 1.3
Power stability
12 hrs		 < 1 % < 1 %
Dimensions 80 cm x 120 cm 80 cm x 120 cm

Performance

Applications

Downloads

FAQ

Do you have customer references?

Yes, the White Dwarf is already installed and tested by many labs. Please contact us, we are happy to share specific references to your application. You can find a first overview of scientific publications from our users below.

How many outputs does the White Dwarf hybrid provide?

The White Dwarf hybrid can offer up to three outputs: 960 nm, 1300 nm and 1035 nm. The outputs can be configured to operate simultaneously or to be switchable. Please contact us for customization options.

At which repetition rate does the White Dwarf hybrid operate?

Our White Dwarf hybrid version can be configured at any single repetition rate between 1 and 5 MHz. The maximum average power is available at the configured repetition rate. Lower repetition rates can be chosen using the built-in pulse-picker. This provides a constant pulse energy at correspondingly lower average power. Example: White Dwarf operating at 2 MHz and 2.5 µJ delivers 5 W; it can be down-picked to 1 MHz and 2.5 µJ delivering 2.5 W.

Who installs the White Dwarf?

Our service team will install the pump laser and the OPCPA at the customer’s site. Users will receive training on the operation of the White Dwarf.

Is the pump laser included in the White Dwarf?

Yes, we offer the full package including pump laser and OPCPA. The pump laser is integrated into the OPCPA housing on a shared thermally managed breadboard offering a robust one-box solution.

Publications

  • May 2, 2019
    Weisenburger et al., Volumetric Ca2+ Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy, Cell (2019)
    https://doi.org/10.1016/j.cell.2019.03.011
  • September 30, 2021
    Streich, L., Boffi, J.C., Wang, L. et al. High-resolution structural and functional deep brain imaging using adaptive optics three-photon microscopy. Nat Methods 18, 1253–1258 (2021).
    https://doi.org/10.1038/s41592-021-01257-6
  • March 6, 2024
    Jason Manley, Jeffrey Demas, Hyewon Kim, Francisca Martínez Traub, Alipasha Vaziri, Simultaneous, cortex-wide dynamics of up to 1 million neurons reveal unbounded scaling of dimensionality with neuron number, Neuron 2024
    https://doi.org/10.1016/j.neuron.2024.02.011
  • December 21, 2023
    Che-Hang Yu, Yiyi Yu,…, Alipasha Vaziri,…, David Fitzpatrick,…, Prakash Kara,…, Ikuko T. Smith & Spencer LaVere Smith, The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo, Nature Methods 2023
    https://doi.org/10.1038/s41592-023-02098-1
  • May 15, 2024
    Bellafard, A., Namvar, G., Kao, J.C. et al. Volatile working memory representations crystallize with practice. Nature 629, 1109–1117 (2024)
    https://doi.org/10.1038/s41586-024-07425-w

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