White Dwarf 3p – three photon microscopy laser
Laser for 3-photon deep-tissue imaging at highest frame-rates
- laser wavelength: 1300 nm and 1700 nm
- repetition rate: up to 5 MHz
- average power: up to 5 W
- high-speed or high-resolution deep imaging
- based on industrial Yb femtosecond laser
Introduction
High performance femtosecond laser for three-photon microscopy (3p microscopy)
The White Dwarf 3p is a femtosecond laser system specially designed for three-photon microscopy offering highest performance and robustness.
With the highest peak power available for 3-photon microscopy, the White Dwarf allows neuroscientists to discover new frontiers in deep brain imaging. Additionally, the one-box solution offers compactness and robustness.
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Features
High power for fast and deep imaging
> 5 W average power after compressor
Proven in the field
Trusted by 30+ neuroscience labs worldwide
Reliability
Robust one-box design
1035 nm output
Output for optogenetics optionally available
Specs
| Specifications | WD-1300S/1300/1300-pro | WD-1300-1700 | WD-1300-1700-pro | WD-1300-1700-ultra | |||
|---|---|---|---|---|---|---|---|
| Switchable 3p Outputs (Central wavelength) | 1300 nm | 1300 nm | 1700 nm | 1300 nm | 1700 nm | 1300 nm | 1700 nm |
| Tuning range (nm) | — | 1250 – 1350 nm | 1650 – 1750 nm | 1250 – 1350 nm | 1650 – 1750 nm | 1250 – 1350 nm | 1650 – 1750 nm |
| Avg. Power | 1.5 W / 3 W / 5 W | > 1.5 W | > 1 W | > 3 W | > 2 W | > 4.5 W | > 3 W |
| Pulse duration FWHM | < 50 fs | < 50 fs | < 65 fs | < 50 fs | < 65 fs | < 50 fs | < 65 fs |
| Dispersion Compensation | up to -12,000 fs² | up to -12,000 fs² | up to -12,000 fs² | up to -12,000 fs² | up to -12,000 fs² | up to -12,000 fs² | up to -12,000 fs² |
| Rep rate | Up to 5 MHz | 1 MHz | 1 MHz | up to 2 MHz | up to 2 MHz | up to 2 MHz | up to 2 MHz |
| Pulse energy (@ 1 MHz) | 1.5 µJ / 3 µJ / 5 µJ | > 1.5 µJ | > 1 µJ | > 3 µJ | > 2 µJ | > 4.5 µJ | > 3 µJ |
| AUX Output (1035nm) | upon request | upon request | upon request | upon request | |||
Performance
Applications
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Volumetric brain imaging
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Scanning temporal focusing microscopy (sTeFo)
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Adaptive optics (AO)
FAQ
Publications
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December 21, 2023Che-Hang Yu, Yiyi Yu,…, Alipasha Vaziri,…, David Fitzpatrick,…, Prakash Kara,…, Ikuko T. Smith & Spencer LaVere Smith, The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo, Nature Methods 2023
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June 21, 2023Marc Cicero Schubert, Stella Judith Soyka et. al., Deep intravital brain tumor imaging enabled by tailored three-photon microscopy and analysis
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November 28, 2022Klioutchnikov, A., Wallace, D.J., Sawinski, J. et al., A three-photon head-mounted microscope for imaging all layers of visual cortex in freely moving mice, Nat Methods (2022).
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September 30, 2021Streich, L., Boffi, J.C., Wang, L. et al. High-resolution structural and functional deep brain imaging using adaptive optics three-photon microscopy. Nat Methods 18, 1253–1258 (2021).
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May 2, 2019Weisenburger et al., Volumetric Ca2+ Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy, Cell (2019)


















