High performance femtosecond laser for three-photon microscopy (3p microscopy)
The White Dwarf is a femtosecond laser system specially designed for three-photon microscopy offering highest performance and robustness.
With the highest peak power available for 3-photon microscopy, the White Dwarf allows neuroscientists to discover new frontiers in deep brain imaging. Additionally, the one-box solution offers compactness and robustness.
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Yes, the White Dwarf is already installed and tested by many labs. Please contact us, we are happy to share specific references to your application. You can find a first overview of scientific publications from our users below.
The White Dwarf 3p can offer up to two outputs: 1300 nm and 1035 nm. The system can be designed to offer all outputs simultaneously or switchable between different outputs. Please also check our White Dwarf-dual and White Dwarf-hybrid for additional output channels.
Our White Dwarf 3p version can be configured at any single repetition rate between 1 and 5 MHz. The maximum average power is available at the configured repetition rate. Lower repetition rates can be chosen using the built-in pulse-picker. This provides a constant pulse energy at correspondingly lower average power. Example: White Dwarf operating at 2 MHz and 2.5 µJ delivers 5 W; it can be down-picked to 1 MHz and 2.5 µJ delivering 2.5 W.
Yes, we offer the full package including pump laser and OPCPA. The pump laser is integrated into the OPCPA housing on a shared thermally managed breadboard offering a robust one-box solution.
Publications
December 21, 2023
Che-Hang Yu, Yiyi Yu,…, Alipasha Vaziri,…, David Fitzpatrick,…, Prakash Kara,…, Ikuko T. Smith & Spencer LaVere Smith, The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo, Nature Methods 2023
Klioutchnikov, A., Wallace, D.J., Sawinski, J. et al., A three-photon head-mounted microscope for imaging all layers of visual cortex in freely moving mice, Nat Methods (2022).
Streich, L., Boffi, J.C., Wang, L. et al. High-resolution structural and functional deep brain imaging using adaptive optics three-photon microscopy. Nat Methods 18, 1253–1258 (2021).
