White Dwarf 2p – two photon microscopy laser
Laser for 2-photon high-speed volumetric imaging
- wavelength: 920 nm or 960 nm
- high average power: > 2 W or > 4 W
- high repetition rate: 10 MHz
- suitable for 2-photon high-speed volumetric imaging
- based on industrial grade Yb-based femtosecond laser
Introduction
High performance femtosecond laser for two-photon microscopy (2p microscopy)
The White Dwarf is a femtosecond laser system specially designed for multi-photon microscopy offering highest performance and robustness.
With the highest peak power available for 2-photon microscopy, the White Dwarf allows neuroscientists to exploit advanced multiplexing techniques to image larger volumes at higher speeds. Additionally, the one-box solution offers compactness and robustness.
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Features
High power for multiplexing 2-photon imaging
> 4 W average power after compressor at 10 MHz
Proven in the field
Trusted by 20+ neuroscience labs worldwide
Reliability
Robust one-box design
1035 nm output
Output for optogenetics optionally available
Specs
| WD-920 | WD-920-pro | WD-960 | WD-960-pro | |
|---|---|---|---|---|
| Central wavelength | 920 nm | 920 nm | 960 nm | 960 nm |
| Average power | > 2 W | > 4 W | > 2 W | > 4 W |
| Pulse duration FWHM | < 100 fs | < 100 fs | < 100 fs | < 100 fs |
| Dispersion compensation | optionally up to -20.000 fs^2 | optionally up to -20.000 fs^2 | optionally up to -20.000 fs^2 | optionally up to -20.000 fs^2 |
| Pulse energy compressed | > 200 nJ | > 400 nJ | > 200 nJ | > 400 nJ |
| Repetition rate | 10 MHz | 10 MHz | 10 MHz | 10 MHz |
| Beam quality M2 | < 1.3 | < 1.3 | < 1.3 | < 1.3 |
| Power stability 12 hrs |
< 1 % | < 1 % | < 1 % | < 1 % |
| Dimensions | 95 cm x 65 cm | 95 cm x 65 cm | 95 cm x 65 cm | 95 cm x 65 cm |
Performance
Stability
Long-term power stability measured with powermeter (averaged shots) over more than 2 days.
Applications
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Volumetric brain imaging
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Light beads microscopy (LBM) and multi-plexed microscopy
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Scanning temporal focusing microscopy (sTeFo)
FAQ
Publications
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May 15, 2024Bellafard, A., Namvar, G., Kao, J.C. et al. Volatile working memory representations crystallize with practice. Nature 629, 1109–1117 (2024)
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March 6, 2024Jason Manley, Jeffrey Demas, Hyewon Kim, Francisca Martínez Traub, Alipasha Vaziri, Simultaneous, cortex-wide dynamics of up to 1 million neurons reveal unbounded scaling of dimensionality with neuron number, Neuron 2024
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September 30, 2021Streich, L., Boffi, J.C., Wang, L. et al. High-resolution structural and functional deep brain imaging using adaptive optics three-photon microscopy. Nat Methods 18, 1253–1258 (2021).
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August 30, 2021Demas, J., Manley, J., Tejera, F. et al. High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy. Nat Methods (2021).
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May 2, 2019Weisenburger et al., Volumetric Ca2+ Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy, Cell (2019)








