High-resolution deep brain imaging up to a depth of 1.4 mm using White Dwarf OPCPA

A new microscopy technique developed at EMBL in Heidelberg enables highest imaging resolution for in vivo neuronal activity measurements deep in the brain, driven by a Class 5 Photonics White Dwarf OPCPA.

Indirect adaptive optics (AO) in combination with three-photon microscopy reaches near-diffraction-limited resolution of very fine structures in the hippocampus up to a depth of 1.4 mm.